Depressive feelings, anxiety, irritability, mental fatigue, panic attacks, obsessive thoughts and ruminations may not be helped enough (or at all) with conventional psychiatric treatment which includes medication and psychological therapies. Holistic therapies take the additional step of addressing neurotransmitters with amino acids and add in healthy eating. But our feelings, emotions, spirituality, physical body and brain are more complex than these interventions suggest. What is overlooked and not addressed at all are the physiologic causes of these symptoms. Physiological causes include inflammation, glucose instability, hormonal imbalances and toxins (infections, chemical toxins, heavy metals, and biotoxins). There are too few physicians, including psychiatrists, who understand and utilize this information. We do understand this and address these symptoms with a systems biology or functional medicine approach. If traditional treatment for your mental health doesn’t fit with you or what you have tried has not worked a true integrative (functional medicine) approach with a very experienced psychiatrist will be able to help.